Publikációk

2018.09.05.

A "Magas mortalitású tumoros betegségek célzott kezelésére alkalmas biokonjugátumok és moduljaik fejlesztése” című NVKP_16-1-2016-0036 számú projekt eredményei a következő publikációkban jelentek meg:

Molecules 2020, 25, 1599.
- Fodor KJ, Hutai D, Jernei T, Takács A, Szász Z, Sulyok-Eiler M, Harmat V, Oláh Szabó R, Schlosser G, Hudecz F, Kőhidai L, Csámpai A.: Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of their In Vitro Antiproliferative Effects
J Mass Spectrom. 2020, 55: e4641 Open Access
- J Mass Spectrom. 2020, 55: e4641 (Open Access Al-Majidi M, Szabó D, Dókus L, Steckel A, Mező G, Schlosser G.: Energy-resolved HCD fragmentation of daunorubicin-peptide conjugates
Pharmaceutics 12, 576 (2020) Open Access
- Dókus EL, Lajkó E, Randelovic I, Mező D, Schlosser G, Kőhidai L, Tóvári J, Mező G.: Phage Display-Based Homing Peptide-Daunomycin Conjugates for Selective Drug Targeting to PANC-1 Pancreatic Cancer
Soft Matter (2020) Open Access, on-line
- Pethő L, Kasza G, Lajkó E, Láng O, Kőhidai L, Iván B, Mező G.: Amphiphilic drug–peptide–polymer conjugates based on poly(ethylene glycol) and hyperbranched polyglycerol for epidermal growth factor receptor targeting: the effect of conjugate aggregation on in vitro activity
Biomolecules 10, 183 (2020) Open Access
- Biri-Kovács B, Adorján A, Szabó I, Szeder B, Bősze S, Mező G.: Structure–Activity Relationship of HER2 Receptor Targeting Peptide and Its Derivatives in TargetedTumor Therapy
Pathology & Oncology Research (Open Access, on-line)
- Tripodi AAP, Randelovic I, Biri-Kovács B, Szeder B, Mező G, Tóvári J.: In Vivo Tumor Growth Inhibition and Antiangiogenic Effect of Cyclic NGR Peptide-Daunorubicin Conjugates Developed for Targeted Drug Delivery
Magyar Onkológia 63:301-308 (2019)
- Mező G, Dókus L, Schlosser G, Lajkó E, Randelovic I, Biri-Kovács B, Tóvári J, Kőhidai L.: Hasnyálmirigytumort célzó terápiás irányítópeptidek összehasonlítása
Magyar Onkológia 63:290-300 (2019
- Mező G, Biri-Kovács B, Pethő L, Schuster S, Kiss K, Oláhné Szabó R, Randelovic I, Tóvári J.: Célzott tumorterápiára alkalmas peptidhatóanyag konjugátumok szerkezetének optimalizálása
Molecules 2019, 24, 4077
- Jernei T, Duró C, Dembo A, Lajkó E, Takács A, Kőhidai L, Schlosser G, Csámpai A. Synthesis, Structure and In Vitro Cytotoxic Activity of Novel Cinchona—Chalcone Hybrids with 1,4-Disubstituted- and 1,5-Disubstituted 1,2,3-Triazole Linkers
Int J Mol Sci 2019, 5027.
- Pethő L, Murányi J, Pénzes K, Gurbi B, Brauswetter D, Halmos G, Csík G, Mező G.: Suitability of GnRH Receptors for Targeted Photodynamic Therapy in Head and Neck Cancers
Int J Mol Sci 2019, 20, 4763.
- Randelovic I, Schuster S, Kapuvári B, Fossati G, Steinkühler C, Mező G, Tóvári J.: Improved In Vivo Anti-Tumor and Anti-Metastatic Effect of GnRH-III-Daunorubicin Analogs on Colorectal and Breast Carcinoma Bearing Mice
Int J Mol Sci 2019, 20, 4421.
- Lajkó E, Hegedüs R, Mező G, Kőhidai L.: Apoptotic Effects of Drug Targeting Conjugates Containing Different GnRH Analogs on Colon Carcinoma Cells
Természet Világa 2017, 386-389
- Mező G, Kiss K, Biri-Kovács B, Oláhné Szabó R.: Személyre szabott rákgyógyítás
Molecules 2019, 24, 2981. (Open Access)
- Pethő, L.; Mező, G.; Schlosser, G. Overcharging Efect in Electrospray Ionization Mass Spectra of Daunomycin-Tuftsin Bioconjugates
European Journal of Medicinal Chemistry 2019, 176: 105-116
- Sequence modification of heptapeptide selected by phage display as homing devicefor HT-29 colon cancer cells to improve the anti-tumour activity of drug delivery systems
Proceedings of the 35th European Peptide Symposium (26th-31st August 2018, Dublin City University, Ireland)
- Synthesis and biochemical evaluation of GnRH-III-drugconjugates - Sabine Schuster az előadásával 2. díjat nyert el a Young Investigators versenyben
- Structure-activity relationship of HER2 receptor targeting peptide and its derivatives in targeted tumor therapy
- Synthesis and in vitro biological effect of GnRH-protoporphyrin IX conjugates
Pharmaceutics 2018, 10: 223.
- Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification
Beilstein Journal of Organic Chemistry 2018, 14: 2495-2504.
- Comparative cell biological study of in vitro antitumor and antimetastatic activity on melanoma cells of GnRH-III-containing conjugates modified with short-chain fatty acids
Molecules 2018, 23: 2248.
- Ferrocene-Containing Impiridone (ONC201) Hybrids: Synthesis, DFT Modelling, In Vitro Evaluation, and Structure–Activity Relationships
- Supplementary materials